我们是否能够根除动物结核病?
Christian Gortázar1, José de la Fuente2,3, Alberto Perelló2,4
1SaBio Instituto de Investigación en Recursos Cinegéticos IREC (UCLM & CSIC), Ciudad Real, Spain. Christian.Gortazar@uclm.es.
Irish veterinary journal
|September 22, 2023
概括
结核菌菌复合体 (MTC) 可以在环境中传播并感染多种物种,因此需要转向综合控制策略. 现代方法必须涉及农民,扩大监测,并将疫苗接种纳入有效结核病 (TB) 管理.
科学领域:
- 兽医流行病学 兽医流行病学
- 传染性疾病 传染性疾病
- 一个健康,一个健康.
背景情况:
- 结核菌复合体 (MTC) 具有环境生存能力,并感染多种宿主,使结核病 (TB) 控制复杂化.
- 虽然工业化国家经常实现无结核病的地位,但M. bovis感染在全球范围内仍然存在,特别是在低收入和中等收入国家.
- 现有的动物结核病控制计划由于高成本和道德考虑而面临挑战.
研究的目的:
- 倡导结核病流行病学和控制的范式转变,超越单一宿主焦点.
- 为MTC维护和传输提出一个全面的,多主机和环境方法.
- 为复杂的结核病情景概述现代,综合的疾病控制策略.
主要方法:
- 对传输和宿主范围相关的MTC特征的审查.
- 分析全球动物结核病情况和控制计划的局限性.
- 针对MTC的多主机维护社区模型的设想.
主要成果:
- MTC的环境弹性和广泛的宿主热带性创造了复杂的传播动态.
- 建议采用多主机环境系统进行MTC维护,涉及野生动物,家禽和环境.
- 当前的控制策略在复杂的流行病学环境中往往不足.
结论:
- 综合性疾病控制需要一个整体的方法,包括农民,多种宿主物种和环境.
- 现代结核病控制应该从单一工具方法过渡到综合战略,包括生物安全和疫苗接种.
- 协作决策和扩大监督对于有效的MTC管理至关重要.
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