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Updated: Jul 16, 2025

Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
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Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer

Published on: April 13, 2015

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由NUDT21损失诱导的MORC2的替代多基化重编程促进了KIRC的致癌性

Yuqin Tan1, Tong Zheng1, Zijun Su2

  • 1Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

JCI insight
|September 22, 2023
PubMed
概括

替代多基化 (APA) 重编程通过缩短MORC2mRNA驱动癌,促进瘤生长. 用一种反感性寡核酸 (ASO) 恢复NUDT21表达,显示出抗瘤效应.

关键词:
癌症 癌症 癌症 癌症瘤基因是一种瘤基因.在瘤学瘤学.瘤抑制剂 瘤抑制剂

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