牙膏中的粘性来源导致牙膏抗菌效率的差异
Oral health & preventive dentistry
|September 22, 2023
概括
在这种实验室研究中,化 (SnF2) 牙膏与氨基化 (AmF) 结合,与化 (SnCl2) 配方相比,对 Streptococcus mutans 生物膜的抗微生物疗效更高.
科学领域:
- 微生物学 微生物学
- 牙科材料科学 牙科材料科学
- 抗菌剂 抗菌剂 抗菌剂
背景情况:
- 突变性链球菌 (Streptococcus mutans) 是导致牙的主要病因.
- 化 (SnF2) 和化 (SnCl2) 由于其在口腔护理产品中的抗菌特性而闻名.
- 氨基化物 (AmF) 常用于牙膏配方,用于预防虫.
研究的目的:
- 评估和比较实验用牙膏的体外抗菌疗效,使用不同的牙膏来源.
- 评估化与化对Streptococcus mutans生物膜活性的影响.
主要方法:
- 在玻璃盘上培养的Streptococcus mutans生物膜进行了体外研究.
- 生物膜暴露于含有不同性来源 (SnCl2,SnF2) 和氨基化物 (AmF) 的实验牙膏泥.
- 通过96小时的异热微热度测量评估生物膜代谢活性,分析生长速度和滞后时间.
主要成果:
- 与对照组相比,所有测试的牙膏显著增加了生物膜滞后时间和减少了生长速度.
- 含有化 (SnF2) 的牙膏显示出比含有化 (SnCl2) 的牙膏显著更大的抗菌效果.
- 特定的SnF2配方在活性生物膜中降低了61.9%,优于SnCl2配方.
结论:
- 使用化 (SnF2) 与氨基化 (AmF) 结合的牙膏具有最高的抗菌疗效.
- 离子的来源显著影响牙膏配方的抗菌性能.
- 这些发现支持使用基于SnF2的牙膏来加强对Streptococcus mutans生物膜的控制.
更多相关视频
08:20Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
6.4K
09:39A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Published on: December 27, 2016
17.8K
相关概念视频
Antimicrobial Effectiveness
37
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
37
Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Chemical Agents for Microbial Control
49
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
49
Antimicrobial Proteins
1.0K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
1.0K
Biofilms
46
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
46
Minerals
344
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Major...
Major...
344
