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Updated: Jul 16, 2025

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair
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Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair

Published on: September 7, 2017

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VEGF分泌驱动古典MAP2K1+梅洛结中的骨形成

Jules D Allbritton-King1, Jyotirindra Maity1, Amit Patel1

  • 1Clinical and Investigative Orthopedics Surgery Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
|September 22, 2023
PubMed
概括

由于MAP2K1突变,梅洛结症患者表现出过度的骨生长. 这项研究使用诱导的多能干细胞来建模疾病,揭示了血管内皮生长因子 (VEGF) 驱动骨形成增加,提供了潜在的治疗点.

关键词:
梅洛里奥斯托西斯 (Melorheostosis) 是一种矿物化 矿物化 矿物化骨髓质组织组织.在VEGF中,VEGF是VEGF.这些是iPSCs.

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Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate10:32

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