怀孕的季节和脑麻的风险
Haoran Zhuo1,2, Beate Ritz3,4, Joshua L Warren5
1Department of Environmental Health Sciences, Yale School of Public Health, New Haven, Connecticut.
JAMA network open
|September 22, 2023
概括
冬季和春季怀孕的儿童患脑 (CP) 的风险略高. 这表明季节性环境因素可能在CP病因学中起作用,这需要进一步调查.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 大脑 (CP) 是最常见的儿童神经运动残疾,但其原因往往是未知的.
- 调查季节性受孕模式可能会揭示CP的病因风险因素.
研究的目的:
- 为了确定怀孕的月份或季节是否与脑的发生有关.
主要方法:
- 一项大规模的队列研究分析了超过400万名加利福尼亚出生 (2007-2015).
- 怀孕时间是从出生日期和妊娠时间来估计的.
- 经母体和邻居因素调整的波桑回归,以根据受孕季节评估CP风险.
主要成果:
- 冬季或春季怀孕的儿童与夏季怀孕相比,患CP的风险增加了9-10%.
- 具体的几个月,如1月,2月和5月,与较高的CP风险有关.
- 这种联系在社会脆弱的社区更为明显,早产的调解最小.
结论:
- 冬季和春季怀孕与脑风险的适度增加有关.
- 季节性变化的环境因素是CP病因的潜在贡献者,需要进一步研究.
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