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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

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补充的HLH易感性因素汇聚在CD8T细胞过活化上

Emily Landy1,2, Jemy Varghese3, Vinh Dang3

  • 1Department of Immunology, University of Pittsburgh, Pittsburgh, PA.

Blood advances
|September 22, 2023
PubMed
概括

在小鼠中对HLH和MAS的双重敏感性揭示了CD8 T细胞的关键作用. 珀福林缺乏和IL-18协同作用,通过T细胞过活化引起致命的炎症.

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