尼托福兰:目前英国指导的证据是什么?
Eleanor Kashouris1, Amelia Joseph2, Tom Lewis3
1Department of Sociology and Criminology, University of Sussex, Falmer, Freeman Building, Brighton, BN1 9RH, UK.
英国的指导方针建议在无并发性尿路感染 (UTI) 时使用短时间3天的尼托夫兰. 然而,有限的证据支持这种持续时间,这引发了对治疗尿路感染的最佳抗生素处方的问题.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 基于证据的医学基于证据的医学.
背景情况:
- 无并发性尿路感染 (UTI) 通常用抗生素治疗.
- 英国基于证据的指导方针建议为期3天的尼托福兰作为尿路感染的第一线治疗.
- 国际指南显示,对尿路感染治疗持续时间的证据基础的解释各不相同.
结论:
- 针对尿路感染的3天尼特洛黄因疗程的证据基础不是稳固的.
- 将最佳抗生素疗程的长度从其他药物推断到尼特罗黄因可能不合适.
- 确定尿路感染的固定的抗生素持续时间可能不是优化处方的最佳策略,因为临床反应的潜在变化.
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