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震动诱导的白指的暴露-反应关系:不同方法预测流行率的影响

Magdalena F Scholz¹, Anthony J Brammer², Steffen Marburg¹

¹School of Engineering and Design, Technical University of Munich, Boltzmannstraße 15, 85748 Garching, Bavaria, Germany.

Annals of work exposures and health

|September 22, 2023

概括

这项研究分析了工人的振动诱导白指 (VWF) 风险,将插值方法与ISO标准进行比较. 该ISO标准为VWF风险提供了保守的估计,仍然适合工作场所评估.

科学领域:

职业健康职业健康职业健康
流行病学流行病学
生物统计学生物统计学

背景情况:

振动诱导的白指 (VWF) 是一个重要的职业健康问题.
现有的元分析提供了工人群体中VWF流行率的数据.
国际标准,如ISO 5349-1:2001,为手臂振动提供暴露-响应关系.

研究的目的:

使用现有的元分析数据,对VWF流行情况进行综合分析.
为了比较不同的流行率插值方法 (线性和多项式) 与ISO暴露-反应关系.
为了完善对手传动振动暴露的VWF风险评估的理解.

主要方法:

从已发表的研究中对VWF流行数据进行了聚合分析.
用线性和多项式插值将观察到的流行率转换为10%的基准值.
进行回归分析,以构建暴露-响应关系,以便在达到10%VWF流行率的时间内.
导出关系与ISO 5349-1:2001标准的比较.

主要成果:

线性和多项式插值方法都为数据提供了很好的匹配.
与线性插入相比,多项式插入表明10%的VWF患病率的终身暴露略高.
衍生的暴露-反应关系的95%置信区间包括ISO暴露-反应关系.
该ISO标准提供了对VWF在A(8) >4 m/s2.2的发展进行保守估计.

结论:

在工作场所,ISO 5349-1:2001的暴露-反应关系仍然适用于评估手传递的振动.
结合线性和多项式插值方法表明ISO关系是保守的.
需要进一步的研究来解决日常振动暴露量计算的ISO方法中的不一致性.

关键词:

暴露与反应的关系.手臂振动手臂振动的情况患病率的流行情况.振动白手指振动白手指

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