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睡眠规律性比睡眠时间更强烈地预测死亡风险:一项前性队列研究
Daniel P Windred1, Angus C Burns1,2,3,4, Jacqueline M Lane2,3,4,5
1Turner Institute for Brain and Mental Health, School of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia.
Sleep
|September 22, 2023
概括
保持一致的睡眠时间表,称为睡眠规律,显著降低死亡风险. 这种一致性是长寿的更强有力的预测因素,而不仅仅是获得的睡眠量.
科学领域:
- 睡眠科学 睡眠科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 睡眠时间是睡眠健康指南的重点,因为它与死亡率有关.
- 新兴研究表明,睡眠的规律性,或睡眠-觉醒时间的一致性,可能是比持续时间更强大的健康预测因素.
- 睡眠规律对大型客观测量的群体死亡率的影响仍未得到充分研究.
研究的目的:
- 为了比较睡眠规律性和睡眠持续时间对所有原因和特定原因死亡率的预测能力.
- 调查睡眠规律度指数 (SRI) 测量的睡眠规律度与英国大型生物银行队列中的死亡风险之间的关联.
主要方法:
- 计算的睡眠规律性指数 (SRI) 得分来自60,977名英国生物库参与者的超过1000万小时的加速度计数据.
- 在加速度计记录后,追踪死亡结果长达7.8年.
- 利用统计模型调整多个混因素,包括年龄,性别,种族,社会人口统计,生活方式和健康状况.
主要成果:
- 较高的睡眠规律与所有原因 (20%-48%),癌症 (16%-39%) 和心脏代谢 (22%-57%) 死亡风险明显降低有关.
- 与睡眠时间相比,睡眠的规律性是所有原因死亡率的更强有力的预测因素.
- 这些关联在前四个SRI五分位数中与最不规则的五分位数相比仍然显著.
结论:
- 睡眠的规律性是死亡风险的关键预测因素,可能比睡眠时间更重要.
- 一致的睡眠和清醒时间是改善公共健康和提高生存率的重要,可行的目标.
- 对睡眠规律的客观测量为评估和减轻死亡风险提供了有价值的工具.
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