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Updated: Jul 16, 2025

Neutrophil Isolation and Analysis to Determine their Role in Lymphoma Cell Sensitivity to Therapeutic Agents
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通过EGR1介导的代谢重编程到氧化酸化有助于B细胞淋巴瘤中IBRUTINIB耐药性

Yunxia Liu1,2, Shuichi Kimpara1,2, Nguyet M Hoang1,2

  • 1Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Blood
|September 22, 2023
PubMed
概括

早期生长反应基因1 (EGR1) 通过重编程新陈代谢,驱动淋巴瘤中的易布鲁替尼抗性. 用甲福明或IM156向氧化酸化克服了这种抗性,为复发或耐药B细胞恶性瘤患者提供了新的治疗策略.

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