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Updated: Jul 16, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Published on: November 5, 2021

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SARS-CoV-2 变种发展出融合的策略来重塑宿主反应

Mehdi Bouhaddou1, Ann-Kathrin Reuschl2, Benjamin J Polacco3

  • 1Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA, USA; Institute for Quantitative and Computational Biosciences (QCBio), University of California, Los Angeles, Los Angeles, CA, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA.

Cell
|September 22, 2023
PubMed
概括

通过改变病毒和宿主因素,SARS-CoV-2 变种也发展出类似的策略来逃避宿主免疫力. 奥米克朗亚型在抑制免疫反应方面表现出不同程度的成功,突出显示病毒的持续演变.

关键词:
冠状病毒天生的免疫力蛋白与蛋白的相互作用蛋白质组学系统生物学转录组学变种病毒与宿主之间的相互作用

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