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Updated: Jul 16, 2025

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
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Published on: July 16, 2021

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替代拼接的失调是家族性肌缩侧面硬化症中突触缺陷的基础

Veronica Verdile1, Ramona Palombo2, Gabriele Ferrante3

  • 1Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis 6, 00135 Rome, Italy; Division of Experimental Neuroscience, IRCCS Fondazione Santa Lucia, Via del Fosso di Fiorano 64, Rome 00143, Italy.

Progress in neurobiology
|September 22, 2023
PubMed
概括

突触基因的改变拼接在家族性肌缩侧面硬化症 (ALS) 运动神经元中很常见. 异常的Sam68蛋白功能有助于这些拼接变化,可能导致ALS病理.

关键词:
另一个替代拼接.肌缩性侧面硬化症 (AMLS) 是一种疾病.这就是Sam6868的原因.

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