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炎症诱导的氧化通过降低脂肪细胞中Sp1转录活性来抑制PPARα的表达和功能

Jungin Kwon1, Yumeko Aoki1, Haruya Takahashi1

  • 1Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011, Japan.

Biochimica et biophysica acta. Gene regulatory mechanisms
|September 22, 2023
PubMed
概括

氧化 (NO) 通过抑制Sp1活性,抑制脂肪细胞中氧酶增殖器激活受体α (PPARα) 基因表达. 这种机制可能解释了肥胖和炎症中PPARα的减少.

关键词:
脂肪组织的脂肪组织.细胞内膜网膜应激压力炎症 炎症是一种炎症.氧化氧化是什么?这是一种PPARα.这就是Sp1 Sp1 Sp1 的意思.

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