在2019年冠状病毒疾病或2019年冠状病毒疾病接种疫苗后,视网膜动脉和静脉封闭的风险
Hyo Song Park1, Nang Kyeong Lee2, Christopher Seungkyu Lee3
1Department of Ophthalmology, College of Medicine, Soonchunhyang University, Cheonan, South Korea; Department of Ophthalmology, Soonchunhyang University Hospital Bucheon, Bucheon, South Korea.
Ophthalmology
|September 22, 2023
概括
在COVID-19感染或接种疫苗后,视网膜动脉和静脉封闭很少发生. 在接受mRNA-1273疫苗的妇女中,观察到视网膜动脉封闭风险的潜在增加,但需要进一步研究.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 和血管事件之间的关联,包括视网膜动脉封闭 (RAO) 和视网膜静脉封闭 (RVO),仍然是研究领域.
- 了解COVID-19感染或接种疫苗后RAO和RVO的发生率对于公共卫生和患者管理至关重要.
研究的目的:
- 为了确定COVID-19诊断或接种疫苗后新的RAO和RVO的发生率.
- 将这些发病率与没有COVID-19或接种疫苗的对照人群进行比较.
- 分析风险因素和与特定疫苗类型的潜在关联.
主要方法:
- 一项全国性的基于人口的队列研究,涉及超过840万名患者.
- 患者被分为三个组:控制组,COVID-19感染组和COVID-19疫苗接种组.
- 使用卡普兰-梅尔方法计算累积发病率,使用考克斯比例危险模型确定危险比率 (HRs).
主要成果:
- 在多变量分析中,与对照组相比,在COVID-19感染或接种疫苗的个人中没有观察到RAO或RVO风险的显著增加.
- 亚组分析表明,在感染之前接种疫苗的个人没有增加风险.
- 在接受mRNA-1273疫苗 (HR 4.65) 的女性中观察到RAO HR升高,尽管原始发病率非常低.
结论:
- 在COVID-19诊断或接种疫苗后60天内,RAO和RVO是罕见的事件.
- 该研究没有发现与COVID-19或其疫苗接种相关的RAO或RVO的整体风险增加.
- 在接种mRNA-1273疫苗的妇女中,RAO的潜在,但罕见的增加风险需要进一步调查.
相关概念视频
Glaucoma: Overview
614
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
614
Angle Closure Glaucoma: Treatment
555
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
555
Photoreceptors and Visual Pathways
6.1K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.1K
Open Angle Glaucoma: Treatment
474
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
474


