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皮肤制药和化品中的无机纳米粒子:特性,配方开发,毒性和监管问题

Filipa Mascarenhas-Melo¹, Ankita Mathur², Sivasubramanian Murugappan³

¹Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Coimbra, Portugal; REQUIMTE/LAQV, Group of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Coimbra, Portugal.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

|September 22, 2023

概括

无机纳米粒子为化品提供独特的特性,增强紫外线保护和配方稳定性. 本综述详细介绍了它们在皮肤保健产品中的应用,特性和安全性.

科学领域:

化品科学化品科学
材料科学材料科学材料科学
纳米技术纳米技术

背景情况:

纳米技术正在化品行业迅速发展,无机纳米粒子 (INPs) 显示出显著的前景.
INP具有独特的物理化学特性,如高折射率和吸收能力,非常适合皮肤应用.
它们的使用在防晒,乳液,奶油和化品中普遍存在,这是因为它们提高了性能和配方的好处.

研究的目的:

审查用于化品和皮肤制药产品的关键无机纳米粒子.
详细介绍这些纳米粒子的物理化学特征和内在特性.
解决与化品应用中的INP有关的安全和监管问题.

主要方法:

关于化品中无机纳米粒子的科学出版物的文献综述.
物理化学性质的分析,包括紫外线吸收和带隙能量.
对纳米粒子使用的安全数据和监管指南的审查.

主要成果:

二氧化和氧化因其紫外线过能力而受到重视,提供无白残留的广泛光谱保护.
其他INP如二氧化,银,金,铜和纳米粒子,以及纳米晶体和量子点,表现出各种有益的特性.
与其他纳米材料相比,INP具有成本效益,增强稳定性和减少皮肤刺激等优势.

结论:

无机纳米颗粒是现代化品配方不可或缺的组成部分,提供先进的功能和提高产品性能.
对其特性和安全性的持续研究对于皮肤制药和化品行业的负责任创新至关重要.
了解安全和监管环境对于INP在消费品中的广泛和安全应用至关重要.

关键词:

化品化品的使用方法皮肤药物制品皮肤药物制品无机纳米粒子是一种无机纳米粒子.有关监管的监管机构有毒性有毒性

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