长距离的FMRP传输和降解是由感觉神经元中的Dynlrb1介导的

Sara Emad El-Agamy1, Laurent Guillaud1, Keiko Kono2

  • 1Molecular Neuroscience Unit, Okinawa Institute of Science and Technology Graduate University, Kunigami-gun, Okinawa, Japan.

PubMed
概括

迪尼因轻链路障碍物1 (Dynlrb1) 调节在感觉轴突中的脆弱X智力障碍蛋白 (FMRP) 运输. Dynlrb1控制FMRP功能,影响mRNA翻译和神经系统疾病中的神经元生存.

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