降低聚甲基甲酸骨水泥度延长了体外工作和设置时间
Lauren K Luedke1, Hussni O Mohammed2, Norm G Ducharme1
1Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.
American journal of veterinary research
|September 22, 2023
概括
稀释聚甲基甲酸 (PMMA) 骨头水泥延长了其在马身上潜在使用的工作和设置时间. 峰值温度各不相同,但两种最高度的热量表现相似.
科学领域:
- 生物材料科学是生物材料的科学.
- 兽医手术 兽医手术是一门兽医手术.
- 聚合物化学 聚合物化学
背景情况:
- 聚甲基甲酸 (PMMA) 骨在各种医疗应用中使用.
- 马的声增强带来了独特的挑战,需要专门的生物材料.
- 了解稀释PMMA的物理性质对于其安全有效的应用至关重要.
研究的目的:
- 为了评估稀释的PMMA骨水泥的设置和温度特性.
- 确定PMMA适用于马的体外声增大.
- 为了确定所需的工作和设置时间的最佳度.
主要方法:
- 准备了四种稀释的PMMA骨水泥与PMMA粉末 (15-30毫升) 的不同体积在10毫升的溶剂.
- 使用数据记录器测量了设置时间 (set),峰值温度 (Tmax) 和到峰值温度的时间 (tmax).
- 使用18尺脊柱针和注射器评估了可注射性和工作时间 (twork).
主要成果:
- 峰值温度在56°C至101°C之间,随着PMMA度的增加而增加.
- 随着PMMA度的增加,设置时间,工作时间和达到峰值温度的时间都减少了.
- 在两种最高度 (25和30毫升PMMAp) 之间没有发现高峰温度的显著差异.
结论:
- 较低度的PMMA骨提供更长的工作和设置时间.
- 稀释PMMA的峰值温度依赖于度,在较高度下,差异变小.
- 需要进一步的体内研究来证实稀释PMMA对马类声增大功效.
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