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创伤性脑损伤后心血管疾病的长期风险:查和预防

Saef Izzy¹, Rachel Grashow², Farid Radmanesh³

¹Divisions of Stroke, Cerebrovascular, and Critical Care Neurology, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Football Players Health Study at Harvard University, Boston, MA, USA.

The Lancet. Neurology

|September 22, 2023

概括

创伤性脑损伤 (TBI) 会增加患慢性心血管疾病的风险. 创伤后的早期查可以减少长期的健康问题,改善患者的生活质量.

科学领域:

神经学神经学
心血管医学心血管医学
公共卫生公共卫生

背景情况:

创伤性脑损伤 (TBI) 在运动员,军人和普通人群中很常见.
虽然神经和精神问题是已知的TBI并发症,但与慢性心血管疾病 (CVD) 风险的联系尚未研究.
研究表明,TBI幸存者面临患心血管疾病的风险更高,即使没有先前的健康问题.

研究的目的:

调查TBI与患慢性心血管疾病的风险之间的关联.
探索心血管风险因素在TBI-CVD关系中的潜在调解作用.
突出了解TBI后心血管疾病风险的重要性,以改善患者的治疗结果.

主要方法:

审查现有关于TBI和心血管结果的研究.
分析来自军事和美国式足球队的数据.
检查将TBI与心血管疾病风险因素联系起来的潜在因果途径.

主要成果:

与没有TBI的人相比,TBI患者的慢性心血管疾病风险显著增加.
有证据表明,可修改的心血管风险因素可能会调解大脑损伤和长期神经和心血管疾病之间的关系.
特定群体 (军人,运动员) 的观察证实了这些发现.

结论:

在TBI和慢性心血管疾病风险增加之间存在显著的关联.
在TBI后了解和管理心血管风险因素对于减轻长期发病率和死亡率至关重要.
建议在TBI患者心血管疾病的积极查和管理策略,以改善生活质量.

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