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在COVID大流行期间,抑制日内分析性饮食的有害影响
Georges Kosmadakis1, Aura Necoara1, Fanny Fuentes1
1AURA SANTE, Clermont Ferrand, France.
Clinical nutrition ESPEN
|September 22, 2023
概括
在血液透析期间暂停饮食对患者的营养状况产生了负面影响,导致体重,白蛋白和白蛋白前蛋白水平降低. 重新引入餐点纠正了这些营养参数,突出了日内分析营养的重要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床营养学 临床营养学
- 公共卫生 公共卫生
背景情况:
- 血液透析的末期功能衰竭患者面临营养不良,发病率和死亡率的高风险.
- 节日内分析性饮食对于营养状况至关重要,但存在低血压的风险.
- 作为安全措施,COVID-19大流行导致透析中心的饮食暂停.
研究的目的:
- 评估暂停内透析饮食对血液透析患者营养参数的影响.
- 评估这些营养变化在重新引入食后的可逆性.
主要方法:
- 追溯性,多中心交叉研究设计.
- 监测的营养参数包括干重量,C反应蛋白 (CRP),血清,血清酸盐,白蛋白,前白蛋白和正常化蛋白质代谢比率 (nPCR).
- 在12个月内收集的数据:在餐前,餐期间和餐后.
主要成果:
- 饮食悬浮剂显著降低了干重量,血清白蛋白,白蛋白前和nPCR.
- 血清CRP,和酸盐水平没有显著变化.
- 重新引入餐带来了所有研究的营养参数的显著纠正.
结论:
- 在COVID-19大流行期间暂停内透析饮食对血液透析患者的营养状况产生了不利影响.
- 内部分析营养对于维持该群体的充足营养参数至关重要.
- 恢复日内分析性饮食有效地扭转了负面的营养结果.
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