揭开胃肠道腺瘤的观察者间变异性:美国和韩国病理学家的当代研究
Richard R Pacheco1, Hyunki Kim2, Won-Tak Choi3
1Pathology and Laboratory Medicine, Albany Medical Center, Albany, New York, USA.
Journal of clinical pathology
|September 22, 2023
概括
美国和韩国病理学家之间的胃肠道瘤活检的诊断方法不同,共识会议可能弥合这些差异. 这项研究突出了解释胃和结肠直肠活检的观察者间变异性.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 胃瘤活检评估的观察者间变异性在西方和东方病理学家之间得到了记录.
- 以前的研究主要集中在日本病理学家身上,在理解美国与韩国病理学家的变化方面存在差距.
研究的目的:
- 调查美国和韩国病理学家之间的胃和结肠直肠瘤活检解释的观察者间变异性.
- 为了比较这两个群体之间的诊断标准和共识水平.
主要方法:
- 十位胃肠道病理学家 (5名美国人,5名韩国人) 评估了100张扫描的活检图像 (50张胃,50张结肠直肠).
- 病理学家填写了问卷,通过多数同意来确定共识.
- 计算了集团间 (科恩的卡帕) 和集团内部 (弗莱斯的卡帕) 的协议.
主要成果:
- 这两组在74%-100%的案例中都达到了共识.
- 集团间协议显示出轻微到完美的可靠性 (κc=0.049-1.000).
- 韩国病理学家专注于细胞架构缺陷 (胃) 和并发性肌内瘤 (结肠直肠),而美国病理学家则强调腺癌诊断的肌层侵袭和脱.
结论:
- 韩国病理学家对胃肠道瘤的诊断方法与东方/日本病理学家一致.
- 在反映可靠性方面,共识指标比kappa统计数据更有效.
- 共识会议可能有助于减少西方和东方病理学家之间的诊断差异.
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