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支持当天诊断和治疗当前C型肝炎病毒感染所需的工具
Gregory P Fricker1, Marc G Ghany2, Jorge Mera3,4
1Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
The Journal of infectious diseases
|September 22, 2023
概括
同一天诊断和治疗C型肝炎病毒 (HCV) 可以提高治疗率. 这种方法需要新的照顾点工具和更好的资源利用,以消除HCV.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 目前对型肝炎病毒 (HCV) 的多日诊断和治疗限制了患者获得直接作用抗病毒药物的机会.
- 在被诊断出HCV感染者和接受治疗者之间存在很大的差距,这阻碍了消除努力.
研究的目的:
- 倡导转向同一天诊断和治疗HCV消除的范式转变.
- 确定诊断工具和资源管理方面的必要进展,以改善HCV治疗的准入.
主要方法:
- 审查当前的HCV诊断和治疗模式.
- 确定对当天诊断和治疗模式的要求,包括点治疗 (POC) 测试和资源优化.
主要成果:
- 多日检测和治疗导致患者参与度低于最佳水平.
- 同一天的诊断和治疗需要新的POC测试 (抗原,核酸) 检测HCV,HBV和HIV,不需要静脉血液.
- 加强资源利用,包括扩大HCV治疗准入和简化审批流程至关重要.
结论:
- 为了消除HCV,转向同一天诊断和治疗的模式转变至关重要.
- 实施POC诊断和优化现有资源将大大提高HCV治疗率.
- 这种方法将改善获得护理的机会,特别是在患者医疗保健接触有限的环境中.
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