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Updated: Jul 16, 2025

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
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通过RB1突变抑制YAP对小细胞肺癌转移至关重要

Zhengming Wu1, Junhui Su2, Fu-Long Li3

  • 1Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA.

Nature communications
|September 22, 2023
PubMed
概括

失去了YAP表达驱动小细胞肺癌 (SCLC) 的转移. 胺HDAC抑制剂恢复YAP,抑制SCLC的传播,并改善小鼠的生存率.

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