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在低风险期怀孕中选择性劳动诱导的新生儿结果
Frida Bengtsson1, Cecilia Ekéus2, Amelie Hagelroth2
1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. frida.bengtsson@regionvastmanland.se.
Scientific reports
|September 22, 2023
概括
选择性劳动诱导 (IOL) 与新生儿并发症 (如败血症和) 的增加有关,尽管死亡风险仍然相似. 医疗保健提供者在低风险怀孕中进行IOL时应谨慎行事.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 公共卫生 公共卫生
背景情况:
- 近年来,劳动诱导率显著增加.
- 之前关于选择性诱导分娩 (IOL) 和新生儿结果的研究提出了相互矛盾的发现.
- 需要澄清与IOL相关的内在新生儿风险.
研究的目的:
- 调查选择性诱导分娩和新生儿并发症之间的关联.
- 为了比较低风险单胎怀孕的新生儿结果,选择性IOL与自发分娩发作相比.
主要方法:
- 基于人口的队列研究,使用瑞典医学出生登记册 (1999-2017) 的数据.
- 纳入标准:怀孕37周0天至41周6天之间的低风险单子妊娠.
- 选择性诱导组和自发性分娩开始组之间的比较.
主要成果:
- 在1999年至2017年期间,选择性IOL的发生率从7.2%上升到16.4%.
- 选择性IOL与胆膜炎,细菌性败血症,内出血,辅助呼吸,超白血症,低Apgar分数和新生儿发作的几率比率更高有关.
- 两组之间没有观察到死亡结果的显著差异.
结论:
- 诱导分娩与新生儿并发症风险增加有关.
- 虽然在这个观察性研究中无法确定因果关系,但对这些风险的认识至关重要.
- 在低风险怀孕中,选择性IOL应谨慎进行.
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