建筑环境微生物组在建造和调试后从户外转移到与人类相关的社区
Gregory R Young1,2, Angela Sherry1,2, Darren L Smith3,4
1Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle, NE1 8ST, UK.
Scientific reports
|September 22, 2023
概括
在新建筑中细菌群落的初始组装显著减少了微生物多样性,并在调试后改变了结构. 人类活动驱动室内微生物的选择,减少室外影响,丰富人类相关的细菌.
科学领域:
- 微生物学 微生物学
- 环境科学 环境科学
- 建筑科学 建筑科学
背景情况:
- 建筑环境的微生物群对人类健康产生影响.
- 之前的研究重点是调节现有的微生物群落.
- 在新建筑中微生物群落的初始组装仍然未被探索.
研究的目的:
- 在建造新建筑环境期间调查细菌社区的获取和发展.
- 描述微生物群落在新建建筑中的初始聚集.
主要方法:
- 使用高通量目标测序.
- 进行微生物采样,从地点识别到调试和使用.
- 随着时间的推移,分析了细菌的丰富性,多样性和社区结构.
主要成果:
- 在投入使用后,细菌的丰富性和多样性显著下降 (P < 0.001).
- 社区结构发生了重大变化 (R2 = 0.14; P = 0.001),室内空间的环境选择增加.
- 室内社区变得富有与人类相关的属 (例如,Escherichia,Pseudomonas,Klebsiella),室外的影响减少了12% (P = 2.00 × 10−15).
结论:
- 这项研究首次描述了建筑环境中最初的细菌社区组合.
- 调查结果显示,在建造和人类占领后,微生物群落发生了显著的变化.
- 结果将为未来的策略提供信息,以调节建筑环境微生物群以获得健康益处.
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