在患有先天性心脏病的患者中对左心房硬度的术后评估
Hideharu Oka1, Kouichi Nakau2, Yuki Shibagaki2
1Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka-Higashi, Asahikawa, Hokkaido, 078-8510, Japan. oka5p@asahikawa-med.ac.jp.
Heart and vessels
|September 22, 2023
概括
手术后先天性心脏病患者经常表现出左心房 (LA) 硬度增加,这表明未来LA功能障碍的风险更高. 早期发现LA硬度对于管理这些患者至关重要.
科学领域:
- 心脏病学 心脏病学
- 心脏生理学 心脏生理学
- 医疗成像医学成像
背景情况:
- 左心房 (LA) 刚性是LA重塑的一个关键因素.
- 在术后先天性心脏病 (CHD) 患者中,LA度的研究不足.
研究的目的:
- 在为先天性心脏病进行手术后的患者中评估左心房刚性.
- 评估该人口中LA硬度升高的患病率和与年龄相关的趋势.
主要方法:
- 利用肺动脉形压力波形从心脏导管以测量压力范围 (v波到x低谷).
- 通过将压力范围除以来自心声学的LA储应变来计算LA刚度.
- 包括75名患者 (67名心血管疾病,8名对照患者),年龄在10-41岁之间.
主要成果:
- 与对照组相比,术后心脏病患者的LA硬度显著增加 (0.28±0.17对比0.13±0.03,p=0.001).
- 在37%的青少年,73%的20多岁患者和25%的30岁以上患者中观察到LA硬度升高.
- 所有LA储菌株<20%的患者都有LA硬度升高.
结论:
- 在CHD手术后的年轻患者中,左心房硬度经常升高.
- 升高的LA度表明,在心脏病患者中,未来可能出现LA功能障碍.
- 监测LA硬度对于术后心脏病患者的风险分层和管理很重要.
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