在卵巢癌中HER2和CD47CAR巨细胞的应用

Yizhao Chen1, Xiangling Zhu1, Hanze Liu2

  • 1Institute of Clinical Pharmacology, Key Laboratory of Anti-Inflammatory and Immune Medicine, Anhui Collaborative Innovation Center of Anti-Inflammatory and Immune Medicine, Anhui Medical University, Ministry of Education, #81 Meishan Road, Shushan District, Hefei, China.

PubMed
概括

针对HER2或CD47的化学抗原受体巨细胞 (CAR-Ms) 显示出对抗卵巢癌的前途. 在临床前模型中,这些CAR-M有效地细胞癌细胞,促进T细胞反应,并减少瘤.

相关概念视频

Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...