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相关概念视频

The Micturition Reflex01:26

The Micturition Reflex

699
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
699
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

126
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
126
Disorders of the Urinary System01:20

Disorders of the Urinary System

348
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
348
Urinary Bladder01:23

Urinary Bladder

871
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
871
Physiology of Urine Formation01:24

Physiology of Urine Formation

4.4K
Urine formation is an essential function of the human body. It plays a critical role in maintaining homeostasis by regulating the volume and composition of body fluids. The kidneys, the primary organs involved in this process, filter blood to remove waste products and excess substances, ultimately producing urine.
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
4.4K
Nursing Assessment of the Genitourinary System I: Health History01:21

Nursing Assessment of the Genitourinary System I: Health History

27
The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
27

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相关实验视频

Updated: Jul 16, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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Detrusor Underactivity Model in Rats by Conus Medullaris Transection

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衰老和尿路控制:脑膀轴的变化

Cara C Hardy1, Ron Korstanje1

  • 1The Jackson Laboratory, Bar Harbor, Maine, USA.

Aging cell
|September 23, 2023
PubMed
概括

尿路老化导致老年人膀控制和组织反应能力下降. 需要对脑膀轴进行更多的研究,以改善泌尿功能障碍的治疗方法.

科学领域:

  • 老年学是指老年学的学科.
  • 神经科学是一个神经科学.
  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科

背景情况:

  • 数以百万计的老年人经历了与年龄相关的膀控制问题,影响生活质量和家庭负担.
  • 目前对老年人尿路功能障碍的治疗选择有限,通常是无效的.
  • 显著需要了解尿路中的衰老过程.

研究的目的:

  • 审查当前关于脑膀轴结构和功能的与年龄相关变化的知识.
  • 为了确定尿路衰老领域的关键知识缺口.
  • 突出未来研究领域,以改善理解和治疗.

主要方法:

  • 关于衰老,膀控制和大脑 - 膀轴的综合文献综述.
  • 综合现有关于与尿路衰老相关的结构和功能变化的数据.
  • 确定关键的研究问题和现场未满足的需求.

主要成果:

  • 尿路衰老的特点是组织的响应能力降低,排泄反射的控制受损.
  • 沿脑膀轴观察到功能障碍的信号传递,以及膀壁的结构变化.
  • 现有研究突出显示,在理解与年龄相关的神经和泌尿变化方面存在重大差距.
关键词:
老化的老化 衰老的老化衰老的分子生物学.神经科学 神经科学

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Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
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Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology

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相关实验视频

Last Updated: Jul 16, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

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Real-Time Void Spot Assay
06:39

Real-Time Void Spot Assay

Published on: February 10, 2023

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Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
10:26

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology

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结论:

  • 大脑 - 膀轴与年龄相关的变化有助于老年人尿路功能障碍.
  • 进一步研究衰老如何影响脑膀通信至关重要.
  • 确定与功能结果相关的遗传点对于开发有效疗法至关重要.