同时发生的ASD介导ADHD对亚托匹性皮肤炎和的影响:回顾性队列研究
Karima M Osman1, Pauline Gerard1, Elijah W Hale1
1University of Colorado, Aurora, USA.
Journal of attention disorders
|September 23, 2023
概括
ADHD和ASD诊断与男性和湿疹的增加有关. 虽然患有ADHD的女性的风险增加,但患有ADHD/ASD或单独患有ASD的女性的湿疹风险有所变化或减少,这表明需要针对性别的护肤研究.
科学领域:
- 神经发育障碍 神经发育障碍
- 皮肤病学 皮肤病学
- 流行病学 流行病学
背景情况:
- 注意缺陷/多动症 (ADHD) 和自闭症谱系障碍 (ASD) 经常与皮肤病相关.
- 有限的研究存在于同时发生的ADHD和ASD与常见的皮肤疾病之间的相互作用.
研究的目的:
- 为了研究ADHD,自闭症症,俗和亚托皮炎之间的关联.
- 探索这些关联中的潜在基于性别的差异.
主要方法:
- 使用了TrinetX数据库中的非识别患者记录.
- 创建了四个平衡的队列:ADHD,ASD,ADHD/ASD,以及没有,按性别分层.
- 与对照组相比,研究了这些队列中和湿疹的流行率.
主要成果:
- 患有ADHD或ADHD/ASD的男性表现出更高的发病率. 所有神经变异的男性都显示出湿疹患病率增加.
- 患有ADHD的女性患和湿疹的患病率增加.
- 患有ASD的女性表现出湿疹风险降低,而患有ADHD/ASD的女性没有显著差异.
结论:
- 研究结果表明,男性和女性患有多动症和自闭症的皮肤学风险概况不同.
- 患有自闭症女性的湿疹风险降低需要进一步研究性别特异性皮肤病治疗方法.
- 建议对皮肤护理策略进行进一步的研究,以适应神经发育障碍中的性别差异.
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