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合成多对比晚期加多增强成像使用后对比磁共振指纹

Imran Rashid^1,2, Sadeer Al-Kindi^1,2, Varun Rajagopalan^1,2

¹Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

NMR in biomedicine

|September 23, 2023

概括

这项研究表明,可以从磁共振指纹 (MRF) 数据创建合成晚期加多增强 (LGE) MRI 图像. 这些合成图像,特别是组织优化的类型,在没有额外的扫描时间的情况下,在患有缺血性心肌病的患者中准确地检测心肌瘤痕.

科学领域:

心血管成像 - 心血管成像
磁共振成像 (MRI) 是一种磁共振成像技术.
评估心脏痕的情况

背景情况:

晚期加多增强 (LGE) MRI 是非侵入性心肌痕识别的黄金标准.
传统的LGE-MRI在划分心下内脏痕方面存在局限性,并且取决于操作者.
磁共振指纹 (MRF) 提供了先进的组织表征能力.

研究的目的:

评估从对比后的MRF T1和T2地图生成多对比合成LGE图像的可行性.
与传统的LGE-MRI相比,评估合成LGE图像的诊断性能.
探索新的合成图像对比,以改善痕的分化,可行的心肌和血液池.

主要方法:

15名患有缺血性心肌病的患者在1.5T时接受了传统的LGE-MRI和MRF.
合成LGE图像 (明亮血PSIR,T2准备的PSIR和组织优化) 由MRFT1/T2地图生成.
图像质量,对比度和痕检测率 (每个患者和每个细分) 与传统的LGE-MRI相比较.

主要成果:

合成PSIR和参考LGE图像获得了最高的图像质量得分.
组织优化的合成图像显示了心肌,痕和血液之间的平衡对比.
合成图像的每患者痕检测率为:PSIR (85%),T2-PSIR (62-100%) 和组织优化 (100%).

结论:

从对比后的MRF数据中可以生成合成多对比LGE图像,而不需要额外的扫描时间.
开发的合成LGE成像方法显示了初步可行性,用于评估缺血性心肌病中心肌瘤痕.
组织优化的合成LGE图像为改善痕特征提供了一个有希望的替代方案.

关键词:

心肌病性心脏病 - 心肌病性心脏病晚期加多增强的加多增强磁共振指纹的使用合成成像技术合成成像技术组织特征的表征.

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