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对于早期肺癌的叶叶切除术和细分切除术后的psoas肌肉质量的长期变化

Tetsuya Isaka^1,2, Hiroyuki Ito¹, Tomoyuki Yokose³

¹Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan.

Journal of cachexia, sarcopenia and muscle

|September 23, 2023

概括

与非小细胞肺癌患者的分片切除术相比,分片切除术更好地保留了psoas肌肉质量. 这表明,细分切除术可能有助于预防肺癌手术后的肉症进展.

科学领域:

胸部外科手术胸部外科手术
手术瘤学手术瘤学
老年医学老年医学

背景情况:

分段切除术比非小细胞肺癌 (NSCLC) 的分片切除术更少侵入性.
细分切除术的较低侵入性背后的生理机制尚未完全理解.
这项研究研究了在NSCLC患者的细分切除术和带切除术后的长期psoas肌肉质量变化.

研究的目的:

为了比较长期的psoas肌肉质量变化在NSCLC患者的细分切除和分叶切除后.
为了确定影响psoas肌肉质量损失后手术的因素.

主要方法:

对315名没有复发的NSCLC患者 (阶段0-I) 进行细分切除或分叶切除的回顾性分析.
计算机断层扫描测量了手术后3-4年间在L3处的双边psoas肌面积 (PMA).
统计分析包括t测试,混合ANOVA和多变量逻辑回归.

主要成果:

分隔切除组与分隔切除组 (P < 0.001) 相比,显著减少了psoas肌肉区域 (PMA) 的变化.
从术后1年到3年,PMA显著下降,但在断片切除组中保持稳定.
腹腔切除术,男性性别和开放胸腔切除术是手术后3年显著PMA损失的危险因素.

结论:

细分切除术后,心肌肌肉质量比脑膜切除术后保持得更好.
脑膜切除术与手术后逐渐减少psoas肌肉质量有关.
细分切除术,特别是通过视频辅助胸部手术,可以降低肉症进展的风险.

关键词:

不那么具有侵入性.输卵管切除术 (lobectomy) 是一个切除术.肌肌肉区域的Psoas 肌肉区域体肌肉质量体肌肉质量萨尔科佩尼亚是什么意思萨尔科佩尼亚分段切除术是指分段切除术.

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