大脑衍生的神经营养因子Val66met多态性与更好的注意力和工作记忆性能以及对轻度慢性压力的弹性有关
Michelle Corrone1, Aleshia Nanev1, Isabella Amato1
1School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, Australia.
The European journal of neuroscience
|September 23, 2023
概括
大脑衍生神经营养因子 (BDNF) Val66met基因变异可能提高认知表现,特别是注意力和工作记忆,为大学生提供抗慢性压力的弹性.
科学领域:
- 神经科学是一个神经科学.
- 遗传学 遗传学 是一个
- 认知心理学 认知心理学
背景情况:
- 大脑衍生的神经营养因子 (BDNF) Val66met多态性与压力和认知有关.
- 它在认知脆弱性或应激弹性方面的作用尚不清楚.
研究的目的:
- 为了研究BDNF Val66met多态化对慢性压力下的执行功能的影响.
- 为了检查这种多态性,自主活动和心理兴奋之间的关系.
主要方法:
- 56名健康的大学生完成了压力,兴奋和认知评估.
- 心率变化测量自主活动.
- 一个认知测试电池评估了注意力,决策,视觉学习和工作记忆.
主要成果:
- 在注意力和工作记忆方面,Val/met参与者表现优于Val/val参与者.
- 瓦尔/梅特个体对与压力相关的注意力缺陷有保护作用.
- 在决策或视觉学习方面没有发现显著差异.
- 多态性与生理或心理兴奋无关.
结论:
- 该BDNF Val66met多态性在认知表现中起着选择性的作用.
- 它可能会赋予与压力相关的认知障碍的弹性,特别是注意力和工作记忆.
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