围绕表面修改的和植入物的骨改造的特点
Vasyli B Makarov1, Ninel V Dedukh2, Olga A Nikolchenko3
1CITY CLINICAL HOSPITAL № 16, DNIPRO, UKRAINE.
概括
具有特定表面结构的和植入物显示出有希望的骨质整合. 多层多孔和多孔植入物在动物研究中显示出更高的骨植入物接触率.
科学领域:
- 生物材料科学 生物材料科学
- 整形外科的研究研究.
- 植入物学 植入物学
背景情况:
- 骨质整合对于牙科和骨科植入物成功至关重要.
- 表面结构显著影响植入物与骨的相互作用.
- 3D打印技术可以精确控制植入物表面的地形.
研究的目的:
- 评估和比较不同表面结构的和植入物的骨整合性质.
- 评估3D打印表面修改对骨植入物接触和体积的影响.
主要方法:
- 对60只雄性白鼠进行了组织学和形态学分析.
- 植入具有多层交织毛孔 (300微米) 和粗表面 (>2微米) 的植入物的植入.
- 植入 300 微米孔和 80% 孔隙的植入物作为对照.
主要成果:
- 具有多层孔的植入物 (59.91%) 和植入物 (53.89%) 在30天内显示出明显高于粗 (44.77%) 的骨植入物接触率.
- 在90天后,与粗 (51.26%) 相比,多层 (66.84%) 和 (70.35%) 植入物保持了优越的骨植入物接触.
- 90天后的骨植入体体积最高的是 (51.2%) 和多层 (48.43%),粗的价值较低 (36.88%).
结论:
- 具有300微米多层交织毛孔的植入物和具有300微米毛孔 (80%毛孔) 的植入物显示出有希望的骨质整合.
- 粗表面植入物具有骨整合能力,尽管效果不如其他测试材料.
- 通过3D打印设计的表面地形学显著影响植入物骨整合.
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