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Updated: Jul 16, 2025

Assessment of Mitochondrial Functions and Cell Viability in Renal Cells Overexpressing Protein Kinase C Isozymes
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Assessment of Mitochondrial Functions and Cell Viability in Renal Cells Overexpressing Protein Kinase C Isozymes

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取决于DNA的蛋白激酶催化子单元 (DNA-PKcs) 通过调节线粒体碎片化来驱动动血管新生素II诱导的血管改造

Litao Wang1, Lin Wu1, Yuxin Du1

  • 1Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital Fudan University, Shanghai, 200032, China; National Clinical Research Center for Interventional Medicine, Shanghai, 200032, China.

Redox biology
|September 23, 2023
PubMed
概括

依赖DNA的蛋白激酶催化子单元 (DNA-PKcs) 通过与Drp1相互作用,促进血管重塑和高血压,导致线粒体功能障碍. 向DNA-PKcs可能为心血管疾病提供新的治疗策略.

关键词:
这就是DNA-PKcscs.DRP1 是一个DRP1在高血压的高血压.线粒体碎片化的分裂血管改造是指进行血管改造.

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