核心位置指导感官运动反射幅度跨越环境背景
Emily C Witts1, Miranda A Mathews1, Andrew J Murray1
1Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, W1T 4JG London, UK.
Current biology : CB
|September 23, 2023
概括
平衡的运动纠正受到环境的影响,而不仅仅是物理力量. 来自部的诺拉德仁基信号传递对于这种运动反应的环境调制至关重要.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 感官整合 感官整合
背景情况:
- 有目的的运动依赖于快速的运动纠正,以保持平衡和姿势.
- 这些反应整合了来自身体和环境的感官信息.
- 环境背景,即使没有机械影响,也可以引发运动反应.
研究的目的:
- 研究环境操纵如何影响侧向前庭核 (LVN) 产生的运动纠正.
- 确定从部发出诺亚上腺体信号的作用,以调解环境对运动控制的影响.
主要方法:
- 在小鼠中对LVN的光遗传刺激.
- 行为实验涉及平衡梁和跑步机.
- 药理学操纵的诺亚上腺体信号传递.
主要成果:
- 由LVN生成的运动校正是由周围环境调节的.
- 环境对运动纠正的影响,需要来自状部的诺亚上腺体信号传递.
- 这表明环境感官处理和脑干运动回路之间存在联系.
结论:
- 大脑干的运动校正系统不仅仅是由直接的物理干扰驱动的.
- 通过noradrenergic途径传递的环境背景,显著塑造了运动反应.
- 这提供了对复杂环境中适应性运动控制背后的神经机制的洞察.
相关概念视频
Functional Brain Systems: Reticular Formation
2.0K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
2.0K
Physiology of Respiration II: Neurogenic Control of Respiration
674
The neurogenic control of respiration coordinates various neural networks and pathways to regulate breathing rate and depth, meeting the body's oxygen and carbon dioxide exchange requirements. This system adapts to physiological and environmental conditions, ensuring optimal breathing patterns.
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
674
Neural Regulation of Blood Pressure
2.9K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
2.9K
Neural Regulation
39.5K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.5K
Major Somatic Sensory Pathways
1.0K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.0K
Sleep-Wake Cycles
1.4K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.4K


