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在乳腺癌中,YTHDF1塑造"冷"瘤,并抑制CD8+ T细胞的透和功能

Lanyu Jing1, Kaiwen Zhou1, Zilin Wang1

  • 1Department of Breast Surgery, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, Guangdong, China.

Experimental cell research
|September 23, 2023
PubMed
概括

YTHDF1在乳腺癌中表达高,阻碍抗瘤免疫反应,促进瘤生长. 减少YTHDF1可以增强免疫细胞的活性,改善患者的存活率,从而成为潜在的治疗点.

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