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宫内福利气球和临床冠状腺炎之间的关联在B组链球菌殖民的患者中,他们接受了标准化劳动管理的诱导
Kira A Bromwich1, Jennifer A McCoy1, Alison G Cahill2
1Maternal-Fetal Medicine Research Program, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (Drs Bromwich, McCoy, and Levine).
American journal of obstetrics & gynecology MFM
|September 23, 2023
概括
宫内福利气球对于患有B组链球菌 (GBS) 的患者的宫成熟是安全的. 这项研究发现,在GBS阳性个体使用福利气球时,临床胆炎的风险没有增加.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 怀孕期间的传染病
背景情况:
- 宫内 Foley气球被广泛用于宫成熟.
- 人们担心,使用福利气球的B组链球菌 (GBS) 阳性患者可能会增加临床冠状腺炎的风险.
研究的目的:
- 调查宫内使用福利气球是否会增加患有GBS的患者临床肌炎的风险.
主要方法:
- 一个随机对照试验的二次分析,比较子宫成熟方法.
- 比较福利气球的使用 (单独或与其他药物) 与仅使用米索普罗斯托尔.
- 主要结局:临床胆肌炎. 二级结局:产后母亲感染性发病率和新生儿结局.
- 使用二项式回归来评估GBS作为修饰的状态,并为混因素进行调整.
主要成果:
- 福利气球使用者与非使用者 (12.6%与11.1%,P=.66) 之间临床胆炎发生率没有显著差异.
- GBS状态没有改变福利气球使用和胆肌炎 (aRR 0.87;95% CI 0.45-1.67) 之间的关联.
- 孕产妇感染性发病率和新生儿结局在不同组中是相似的.
结论:
- 福利气球用于宫成熟与患者感染性发病风险的增加无关,包括那些患有GBS定居的患者.
- 研究结果支持福利气球在经过宫成熟的GBS阳性患者的安全使用.
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