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在西班牙加泰罗尼亚的一家初级保健机构中,严重的高甘油三血症的患病率
Emilio Ortega1, Bogdan Vlacho2, Ray Puig Treserres2
1DAP-Cat group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Lipid and Vascular Risk Unit, Endocrinology and Nutrition Department, Hospital Clinic Barcelona, Spain; CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Spain.
过高甘油三血症 (HTG) 影响0.7%的中度至重度和0.2%的重度. 大多数病例与肥胖和不受控制的糖尿病等二次原因有关.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 过高甘油三血症 (HTG) 是心血管疾病和胰腺炎的重要危险因素.
- 它的患病率在世界各地的不同人口中差异很大.
- 了解HTG患病率对于公共卫生战略至关重要.
研究的目的:
- 为了确定西班牙初级保健机构中中度至重度HTG (msHTG) 和重度HTG (sHTG) 的患病率.
- 在这个人群中识别和分类导致HTG的因素.
- 分析HTG患病率随时间的推移的趋势.
主要方法:
- 对2010-2019年临床和实验室数据的回顾性分析.
- 包括具有低脂或甘油三升高作用的药物.
- 对年龄和性别进行调整的物流回归模型,以评估共变量关联.
主要成果:
- 在记录了甘油三水平的个体中,msHTG的发病率为0.7%,sHTG为0.2%.
- 在36-50岁的个人和男性中观察到更高的患病率.
- 肥胖,不受控制的糖尿病和高马-氨基转移酶与msHTG/sHTG有很强的关联.
结论:
- 这项研究量化了在西班牙加泰罗尼亚的初级保健人口中msHTG和sHTG的患病率.
- 二次性原因,包括肥胖和不受控制的糖尿病,是msHTG和sHTG的主要驱动因素.
- 研究结果强调了管理高甘油三血的二次风险因素的重要性.
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