在胃液中患有Ureaplasma的早产和满期婴儿的临床特征
Yoshiichi Abe1, Masanori Inoue2, Kazuhito Sekiguchi2
1Department of Pediatrics, Faculty of Medicine, Oita University, Oita, Japan; Department of Pediatrics, Koseiren Tsurumi Hospital, Oita, Japan.
Pediatrics and neonatology
|September 23, 2023
概括
新生儿暴露于尿液等离子体与更高的孕产妇胆膜炎和特定的婴儿健康问题有关. 这项研究确定了暴露于Ureaplasma的母亲和婴儿的独特临床特征.
科学领域:
- 新生儿研究新生儿研究
- 微生物学 微生物学
- 产科 产科 产科 产科 产科
背景情况:
- 尿液等离子体 spp. 尿液等离子体 spp. 是常见的微生物,在怀孕和新生儿中具有争论的致病性.
- 暴露于Ureaplasma和对母亲或婴儿的不良结果之间的关联,特别是在预产婴儿中,尚不清楚.
- 本研究研究了胃液中具有和没有Ureaplasma的新生儿的临床特征.
研究的目的:
- 调查早产和满期婴儿的临床特征和结果,有或没有Ureaplasma暴露.
- 为了确定与Ureaplasma检测相关的母亲和新生儿的特定临床特征.
主要方法:
- 从47名新生儿的胃液样本使用多重PCR对Ureaplasma spp.进行了分析.
- 对新生儿和母亲的临床数据和结果被追溯评估.
- 特别关注Ureaplasma parvum和Ureaplasma urealyticum的检测. 这是一个很好的方法.
主要成果:
- 尿液等离子体 spp. 尿液等离子体 spp. (所有U. parvum) 在19%的新生儿中检测到.
- 尿质阳性婴儿的母体胆膜炎的发病率更高.
- 过早出生的婴儿显示IgM的升高; 过期的婴儿增加了母亲感染的标志物和不令人放心的胎儿状态. 所有Ureaplasma阳性的极低出生体重的婴儿都患有支气管肺功能失调.
结论:
- 孕妇和胎儿暴露于Ureaplasma与怀孕期间和产后出现不同的临床表现有关.
- 在新生儿中检测Ureaplasma parvum与特定的母亲和婴儿健康指标相关.
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