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在正常眼睛和青光眼中,OCT扫描源和光谱域之间的宽和立方扫描测量的一致性和精度在正常和青光眼中

Huiyuan Hou¹, Nevin W El-Nimri², Mary K Durbin²

¹Topcon Healthcare, 111 Bauer Dr, Oakland, NJ, 07436, USA. hhou@topcon.com.

Scientific reports

|September 23, 2023

概括

这项研究发现,扫描源OCT (SS-OCT) Triton和光谱域OCT (SD-OCT) Maestro设备之间的高精度和优异的一致性用于青光眼的测量. 宽扫描为诊断和管理提供互操作性.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
玻璃眼研究研究玻璃眼研究

背景情况:

光学连贯断层扫描 (OCT) 对于诊断和治疗青光眼至关重要.
对比不同的OCT设备,如扫源OCT (SS-OCT) 和光谱域OCT (SD-OCT),对于临床互操作性至关重要.
评估测量精度和设备之间的一致性可确保可靠的诊断数据.

研究的目的:

评估SS-OCT Triton和SD-OCT Maestro之间的宽扫描测量在正常眼睛和青光眼中的一致性.
评估使用两种OCT设备的宽扫描和立方扫描测量的精度.
为了确定广扫描对玻璃眼评估的潜在临床用处.

主要方法:

测量了环皮状视网膜神经纤维层 (cpRNFL),状细胞层+内状层 (GCL+) 和状细胞复合体 (GCL++).
对于Triton和Maestro,使用了三个操作员/设备配置,随机选择了眼睛和测试顺序.
使用布兰德-阿尔特曼分析和德明回归来评估一致性和精度.

主要成果:

这两种设备在所有厚度测量中都表现出高精度,极限通常低于5微米 (斑点) 和10微米 (光盘).
宽扫描和立方扫描的精度在两种设备中都是可比的.
在Triton和Maestro之间观察到宽扫描的优异一致性,平均差异低于3μm,表明设备的互操作性.

结论:

SS-OCT Triton和SD-OCT Maestro显示出高精度和与眼相关的测量结果的良好一致性.
宽扫描OCT成像证明了设备之间的互操作性,支持其在临床实践中的使用.
单一的宽扫描可能足以进行全面的青光眼诊断和管理,覆盖周围毛囊和黄斑区域.

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