在低化物化学定义介质中培养Vibrio natriegens的高细胞密度培养
Richard Biener1, Thomas Horn2, Alexander Komitakis2
1Faculty of Science, Energy and Building Services, University of Applied Sciences Esslingen, Kanalstraße 33, 73728, Esslingen, Germany. richard.biener@hs-esslingen.de.
Applied microbiology and biotechnology
|September 23, 2023
概括
为Vibrio natriegens开发了一种新的低化物介质,用其他盐取代化. 这一创新可以防止生物反应器腐蚀,并使生物技术应用中的高生物质产量成为可能.
科学领域:
- 生物技术是生物技术.
- 微生物学 微生物学
- 化学工程是化学工程的重要组成部分.
背景情况:
- 维布里奥纳特里根菌是一种性细菌,在非致病性细菌中已知生成时间最快.
- 它的快速增长使其成为生物技术生产的有希望的候选人.
- 对于V. natriegens的传统介质含有高度的盐,导致生物反应器腐蚀.
研究的目的:
- 为V. natriegens开发一种化学定义的介质,其化物含量最小.
- 为了减轻工业生物反应器中的腐蚀问题.
- 优化V. natriegens种植以获得高生物质产量.
主要方法:
- 将化完全替换为二酸,二硫酸盐和酸.
- 保持恒定的总离子度.
- 使用酸盐来防止沉,特别是酸的沉.
主要成果:
- 对V. natriegens成功开发了一种低化物,化学定义的介质.
- 高细胞密度养批量种植实现了超过60gL-1的生物质度.
- 这种新介质可以防止生物反应器金属表面的腐蚀.
结论:
- 开发的低化物介质适合V. natriegens种植.
- 这种媒介解决了工业生物技术中生物反应器腐蚀的挑战.
- 高生物质产量是可以实现的,增强了V. natriegens作为生产菌株的潜力.
关键词:
氨酸酸酸氨酸酸.酸的使用方法腐蚀是一种腐蚀.联邦储备局批量批量高细胞密度培养方式降水量 降水量 降水量具体增长率的具体增长率是什么维布里奥纳特里根斯 (Vibrio natriegens) 是一种天然物质.更多相关视频
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