粘膜类型慢性辅助性中耳炎中的细菌学概况和药物敏感性
Rajesh Maharjan1, Brihaspati Sigdel2, Rajendra Nepali2
1Department of Otolaryngology, Nepal Korea Friendship Municipality Hospital, Thimi.
Journal of Nepal Health Research Council
|September 24, 2023
概括
这项研究确定金黄色葡萄球菌是慢性性中耳炎的最常见原因. 伊米胺证明对孤立的细菌具有100%的有效性,突出显示了它在治疗这种疾病方面的潜力.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 慢性性耳中炎 (CSOM) 通常是由Pseudomonas aeruginosa和Proteus物种引起的.
- 抗生素耐药性需要对CSOM进行培养导向治疗.
- 了解当地的细菌学特征和抗生素敏感性对于有效治疗至关重要.
研究的目的:
- 为了确定CSOM的细菌学概况.
- 评估孤立病原体的抗生素敏感性模式.
- 为CSOM提供适当的抗生素处方指南.
主要方法:
- 从2019年7月到2020年6月进行了一项基于医院的描述性研究.
- 从127名患有慢性耳部泄漏和中 tympanic膜穿孔的患者收集了抽样样本.
- 培养和敏感性测试是按照临床和实验室标准研究所的指导方针进行的.
主要成果:
- 黄金葡萄球菌是最常见的隔离物 (43%),其次是Pseudomonas aeruginosa (23.4%).
- 普罗蒂乌斯奇迹菌 (9.3%) 和大肠杆菌 (8.4%) 也是显著的分离物.
- 所有测试的生物体对伊米佩内姆有100%的敏感性,96.2%对 gentamicin,和95.3%对阿米卡辛.
结论:
- 金黄色葡萄球菌是这个CSOM队列中占主导地位的病原体.
- 伊米,珍塔和阿米卡是针对CSOM分离物的高度有效的抗生素.
- 以培养为导向的抗生素治疗对于对抗CSOM的耐药性至关重要.
相关概念视频
Sputum Studies II: Culture and Sensitivity
377
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
377
Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
225
Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
225
Urine Studies II: Urine Culture and Sensitivity Test
38
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
38


