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胃肠道手术后手术部位感染的细菌学概况及其抗生素

Neha Shrestha¹, Sangita Sharma², Bikal Ghimire³

¹Department of Microbiology, Indira Gandhi Memorial Hospital, Male, Maldives.

Journal of Nepal Health Research Council

|September 24, 2023

概括

手术部位感染常常是由多种耐药性细菌引起的,包括产生大肠杆菌的扩展光谱β-乳糖酶和耐甲西林的金黄色葡萄球菌. 有效的管理需要监测和合理的抗生素使用.

科学领域:

传染性疾病传染性疾病
微生物学微生物学
手术感染手术感染

背景情况:

手术部位感染 (SSI) 是腹部手术的一个重要并发症.
多种耐药细菌的增加使SSI管理变得复杂.
识别致病原体及其耐药性模式至关重要.

研究的目的:

在胃肠道手术后识别导致SSI的细菌病原体.
为了确定孤立细菌的抗生素耐药性模式.

主要方法:

在Tribhuvan大学教学医院接受胃肠道手术的患者的前性研究.
收集和标准处理SSI患者的样本.
细菌病原体的识别和抗微生物敏感性测试,包括检测甲素耐药的金黄色葡萄球菌和扩展光谱β-乳糖酶生产者.

主要成果:

832名患者中有19.5%患上了SSI;125人产生了细菌生长.
大肠杆菌 (29.9%) 是最常见的分离物,ESBL产量为40.8%.
47.4%的金黄色葡萄球菌分离体是对甲基西林耐药的.
在克拉姆阴性 (75.9%) 和克拉姆阳性 (60.4%) 细菌中观察到高水平的多药耐药性.

结论:

实质性的多药耐药细菌负担导致SSI.
及时干预和对细菌抗生素图的强有力的监测是必不可少的.
合理使用抗微生物药物对于制耐药性的出现和传播至关重要.

关键词:

扩展谱β乳糖酶;胃肠道手术;耐美西林黄金葡萄球菌;多药性耐药性;手术部位感染.

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