简要介绍SARS-CoV-2感染及其管理策略:最近的更新
Alakesh Das1, Surajit Pathak1, Madhavi Premkumar1
1Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, Tamil Nadu, 603103, India.
Molecular and cellular biochemistry
|September 24, 2023
概括
COVID-19通过细胞因子激增引起严重疾病,导致器官损伤. 有效的治疗方法和全面的COVID-19后管理策略对于患者的康复和减轻大流行病的危害至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
- 关键护理医学 关键护理医学
背景情况:
- 由于细胞因子激增,COVID-19呈现出各种症状,并可能导致严重的后果.
- 过度释放的炎症性细胞因子 (例如IL-6,TNF-α) 会导致组织损伤和器官功能障碍.
- 管理细胞因子激增及其并发症是COVID-19治疗的关键重点.
研究的目的:
- 审查有效的治疗措施,以减轻COVID-19的严重程度.
- 突出全面的COVID-19后管理战略的重要性.
- 强调需要基于对COVID-19病原体的不断变化的理解而量身定制的治疗方法.
主要方法:
- 审查有关COVID-19治疗方案的现有文献.
- 治疗干预措施的分析,包括皮质类固醇,氨酸和免疫球蛋白.
- 探索新的策略,如药物重新使用和体外药物查.
主要成果:
- 标准化方案包括皮质类固醇,和IV免疫球蛋白用于急性管理.
- 新的策略包括重新定位药物和使用体外查有效抗病毒药物.
- 包括营养和多学科随访在内的COVID-19后护理越来越被认为是至关重要的.
结论:
- 定制的治疗策略对于有效的COVID-19管理至关重要.
- 缓解细胞因子激增对于降低疾病严重程度至关重要.
- 综合管理,包括急性和后急性阶段,对于打击COVID-19至关重要.
相关概念视频
01:28Pneumonia IV: Management
353
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
353
01:30Pneumonia V: Nursing management and Prevention
2.1K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.1K
01:29Chronic Obstructive Pulmonary Disease-V: Management
2.6K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.6K
01:22Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
01:24Cystic Fibrosis: Management
185
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
185
01:30Acute Pancreatitis II: Clinical Manifestations and Management
142
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
142