稀土元素的命运,亚细胞分布和稀土元素在淡水双中在复杂暴露下对生物的影响
Nicolas Lachaux1, Alba Otero-Fariña2, Laetitia Minguez3
1Université de Lorraine, CNRS, LIEC, F-57000 Metz, France; LTSER-Zone Atelier Moselle, F-57000 Metz, France.
The Science of the total environment
|September 24, 2023
概括
稀土元素 (REE) 在淡水双体中积聚,其影响由溶解的有机物减少. 它们的生态毒理学是复杂的,但添加性模型可能适合REE混合物的风险评估.
科学领域:
- 环境毒理学环境毒理学
- 新出现的污染物的生态毒理学.
- 微量元素分析分析
背景情况:
- 稀土元素 (REE) 越来越多地用于技术,引发了人们对它们对环境的影响的担忧.
- 关于REE生物效应的相互矛盾数据需要更深入地了解其生态毒理学.
- 本研究调查了关键REE在相关水生生物体中的环境命运和影响.
研究的目的:
- 评估新 (Nd),加多 (Gd) 和 (Yb) 在Corbicula fluminea中的生物积累和生物效应.
- 为了确定溶解有机物 (DOM) 对REE生物可用性和毒性的影响.
- 为改善环境风险评估提供REE生态毒理学的全面理解.
主要方法:
- 淡水双鱼Corbicula fluminea暴露于1毫克L-1的Nd,Gd和Yb单独和作为混合物96小时.
- 研究REE的命运,分布 (组织和亚细胞水平),以及在DOM的存在和缺席下生物积累.
- 分析生物效应,包括溶酶体大小,和离子调节 (Na+度) 和Ca2+ ATPase活性.
主要成果:
- 双子积累了Nd,Gd和Yb的显著度,由于复杂化,DOM的积累减少了.
- REE的分布因组织而异 ( > 消化腺 > 其他组织 > 血淋巴) 并且主要发生在对金属敏感的有机体和颗粒中.
- Nd,Gd和Yb损害了 lysosome 功能和光离子调节,在单个和混合暴露时观察到类似的效果.
结论:
- 溶解的有机物显著降低了REE的生物可用性和随后的生物积累.
- REEs通过影响细胞结构和生理调节对双产生有毒作用,单个和混合暴露的模式类似.
- 添加性方法很可能适用于评估像Nd,Gd和Yb这样的REE混合物所带来的环境风险.
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