长期护理中的潜在不适当的处方及其与可能的妄想的关系
Colleen Webber1, Christina Milani2, Lise M Bjerre3
1Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Bruyère Research Institute, Ottawa, Ontario, Canada; ICES, Ontario, Canada.
Journal of the American Medical Directors Association
|September 24, 2023
概括
在长期护理中,潜在不适当的处方 (PIP) 是常见的. 较高的PIP病例显著增加了居民之间可能妄的风险.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 在长期护理 (LTC) 环境中,潜在不适当的处方 (PIP) 是一个重大问题.
- 狂妄症是居住在LTC设施中的老年人中常见且严重的疾病.
研究的目的:
- 为了调查安大略省LTC居民中PIP的流行率.
- 在这个人群中检查PIP和可能的妄想之间的关联.
主要方法:
- 基于人口的横截面研究,使用省级卫生行政和LTC评估数据 (RAI-MDS 2.0).
- 使用STOPP/START和Beers标准评估PIP;通过临床评估协议确定可能的妄想.
- 后勤回归模型用于分析PIP和妄想之间的关系.
主要成果:
- 在171,190名LTC居民中,超过一半的人表现出PIP (51.8%通过STOPP/START).
- 可能的患病率随着PIP病例数量的增加而增加.
- 患有3个以上PIP病例的居民患有可能妄的可能性是1.66倍.
结论:
- 在安大略省的LTC居民中,PIP非常普遍.
- 在PIP和可能妄的患病率增加之间存在显著的关联.
- 与中枢神经系统相关的PIP标准显示,与妄想有更强的联系.
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