肝移植接入和结果:肝脏特异性专科护理变化的影响
Yutaka Endo1, Kazunari Sasaki2, Zorays Moazzam1
1Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH.
Surgery
|September 24, 2023
概括
获得肝脏专家的机会会影响肝脏移植登记,但不会影响等候名单的结果. 在服务不足的地区的社会贫困使移植后的移植存活率恶化.
科学领域:
- 肝病学和移植外科手术
- 公共卫生与医疗保健 获取 获取
- 健康的社会经济决定因素
背景情况:
- 获得专门的护理,包括胃肠道学家/肝病学家,对于肝移植至关重要.
- 在获得医疗保健的地理和社会经济差异显著影响患者的肝移植途径.
- 了解这些差异是改善肝移植公平的关键.
研究的目的:
- 评估如何访问胃肠道学家/肝病学家影响肝移植列表.
- 检查专家访问对肝移植等候名单的持续时间和移植后结果的影响.
- 确定导致肝移植差异的因素.
主要方法:
- 2004-2019年使用移植受体科学注册表对肝移植注册者 (年龄大于18岁) 的分析.
- 根据每1000例肝脏相关死亡的县级等候名单注册人数,定义肝移植注册率.
- 区间的结果比较 充足与缺乏肝脏专用护理的地区,控制相关的共变量.
主要成果:
- 在获得肝脏专用护理的机会较差的县,与获得足够护理的县相比,观察到肝移植登记率较低 (137.2对157.6).
- 候候名单死亡率和移植后移植存活率在缺乏和充分获得护理的患者之间是可比的.
- 在接入不便的地区,较高的区域剥夺指数预测了肝移植接受者之间更糟糕的移植存活率.
结论:
- 获得肝脏专用护理的限制与肝脏移植注册率的降低有关.
- 服务不足地区的社会贫困对肝移植后的移植存活率产生了负面影响.
- 解决医疗保健获取差异对于改善肝移植结果至关重要.
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