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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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在"ISCHEMIA"试验后的功能成像.

Suzanne Duhamel1, Théo Pezel2, Jérôme Garot1

  • 1Cardiovascular Magnetic Resonance Laboratory, institut cardiovasculaire Paris Sud, hôpital privé Jacques-Cartier, Ramsay santé, 6, avenue du Noyer-Lambert, 91300 Massy, France.

Archives of cardiovascular diseases
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概括
此摘要是机器生成的。

重血管化对稳定的缺血性心脏病患者,中度至重度缺血症患者的最佳药物治疗没有额外的好处. 本综述总结了ISCHEMIA试验,其局限性,以及临床医生可能误解的情况.

关键词:
慢性冠状动脉综合征 慢性冠状动脉综合征冠状动脉计算机断层扫描血管图谱.功能成像测试功能成像测试伊斯基米亚试验试验心肌缺血是什么意思 心肌缺血是什么意思

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科学领域:

  • 心脏病学 心脏病学
  • 临床试验 临床试验
  • 医疗成像医学成像

背景情况:

  • 以前的COURAGE和BARI 2D等试验表明,对于稳定性缺血性心脏病 (SIHD) 患者来说,再血管化的额外益处没有.
  • 该ISCHEMIA试验调查了SIHD中度至重度缺血症患者的重血管化与最佳医疗治疗.

研究的目的:

  • 总结ISCHEMIA试验的研究结果.
  • 为了突出ISCHEMIA试验的局限性.
  • 警告医疗保健提供者不要误解试验的含义.

主要方法:

  • 随机临床试验比较重血管化加最佳医疗疗 (OMT) 与单独OMT.
  • 纳入标准:SIHD患者在功能测试中患有中度至重度缺血和显著的冠状动脉狭窄.
  • 功能测试包括成像或应力心电图;通过冠状动脉血管学评估的狭窄.

主要成果:

  • 在ISCHEMIA试验中,重血管化和OMT组之间的结果没有显著差异.
  • 这两种策略都产生了类似的重大心血管不良事件发生率.
  • 这一发现适用于中度至重度缺血和严重冠状动脉疾病的患者.

结论:

  • 该ISCHEMIA试验为管理稳定的缺血性心脏病患者提供了关键数据.
  • 这项研究引发了关于功能成像在诊断和治疗决策中的作用的辩论.
  • 需要仔细解释,以避免在临床实践中误用结果.