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视频囊内镜中小肠疾病的患病率在慢性粒状小肠病相关的炎症性肠病中
Sumona Bhattacharya1, Uni Wong2, Mian Khalid1
1Digestive Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
小肠炎症性肠病 (IBD) 在慢性粒状肠病 (CGD) 中很常见. 视频囊内镜 (VCE) 对于诊断CGD患者的小肠疾病,特别是结肠干扰患者,是有用的.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
背景情况:
- 慢性颗粒性肠病 (CGD) 患者有发展炎症性肠病 (IBD) 的风险.
- 在CGD相关的IBD中小肠的参与并没有得到很好的描述.
- 关于诊断小肠疾病的诊断工具在这个人群中的有用性存在有限的数据.
研究的目的:
- 确定患有CGD的患者中小肠疾病的患病率和特征.
- 评估视频囊内镜 (VCE) 对诊断CGD患者小肠疾病的临床实用性.
主要方法:
- 对25名CGD患者的26个VCE进行了回顾性审查,这些患者被评估为胃肠道疾病.
- 分析VCE发现的炎症特征和疾病严重程度,使用囊内镜克罗恩病活动指数.
- 将VCE发现与同时进行的X光学研究和内镜评估进行比较.
主要成果:
- 85%的患者在VCE上表现出小肠炎症发现,包括狭窄,,侵蚀和红斑.
- 在内镜检查或放射检查中,没有发现VCE发现与十二指肠/肠疾病之间的相关性.
- 中度至重度结肠疾病和延长小肠过境时间与VCE中度至重度小肠疾病相关.
结论:
- 小肠IBD在CGD患者中非常普遍.
- VCE是调查CGD相关IBD中小肠疾病的一个有价值的工具.
- 推使用VCE导向诊断,特别是对于现有结肠病的CGD患者.
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