杜克斯家族成员之间的对抗性来自一个祖先有毒的单一家庭主体蛋白质

Darko Bosnakovski1,2, Erik A Toso1,2, Elizabeth T Ener1,2

  • 1Lillehei Heart Institute, University of Minnesota, Minneapolis, MN 55455, USA.

iScience
|September 25, 2023
PubMed
概括

双同源盒 (DUX) 基因家族包括对抗性成员. 鱼sDUX与DUX4共享细胞毒性,而DUXA则提供反抑制,影响着阴茎基因组激活,肌肌肉缩和癌症.

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