使用部分和整个收集,确定电子烟气溶中的化学成分产量,进行比较分析
J Brian Jameson1, Jiaming Wang1, Patrick C Bailey1
1Juul Labs, Inc., Washington, DC, United States.
Frontiers in chemistry
|September 25, 2023
概括
电子尼古丁输送系统 (ENDS) 气溶收集方法影响化学产量测量. 整个囊收集提供了更高的精度,金属,碳酸,和糖醇相比,在设备的使用寿命的部分气泡块收集.
科学领域:
- 环境化学环境化学
- 分析化学 分析化学
- 毒理学 毒理学 毒理学
背景情况:
- 电子尼古丁输送系统 (ENDS) 气溶分析依赖于各种收集策略.
- 对于产品在整个使用寿命期间的ENDS化学成分产量,早期吸气收集的代表性了解有限.
研究的目的:
- 评估不同的气溶收集策略如何影响基于封闭的ENDS中特定化学成分的报告产量.
- 为了确定部分囊收集与整个囊收集的有效性,以评估ENDS气溶成分.
主要方法:
- 分析了选择的化学成分,反映了监管指南中的关键类别.
- 规范化组成部分产生了设备总质量损失 (DML).
- 比较了从部分气泡块集合获得的产量与从整个集获得的产量.
主要成果:
- 主要成分 (propylene glycol,糖醇,尼古丁) 的DML正常化产量是一致的,验证了这些部分收集.
- 某些金属,碳烯化合物和甘油醇的产量在的寿命中显著变化,这取决于化学物质和产品.
- 整个囊收集显示较高的灵敏度和准确性,金属,碳酸,和糖相比,气阻塞方法.
结论:
- 部分囊采集适用于产量稳定的成分,但对其他成分需要验证.
- 最初的吸气块收集不足以准确量化成分,在子的寿命中产量可变.
- 整个囊收集提供了一个更全面,更准确的评估ENDS气溶的化学成分,特别是金属,碳酸和糖醇.
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